Fujisawa, yang sering tak bisa mengendalikan emosinya karena PMS bulanan, akhirnya meledak marah karena sesuatu yang dilakukan oleh rekan kerjanya, Yamazoe. Namun, Yamazoe yang terlihat tak bersemangat meskipun baru saja pindah kerja, ternyata menderita gangguan kecemasan, putus asa, lelah, dan kehilangan semangat hidup. Didukung oleh rekan kerja yang saling memahami, mereka membangun perasaan khusus, bukan teman atau kekasih, tapi lebih seperti sahabat. Tanpa mereka sadari, mereka mulai berpikir mungkin mereka bisa saling membantu meski tidak dalam kondisi yang baik-baik saja.

Fujisawa, who cannot control her PMS induced irritability that comes once a month, ends up exploding in anger one day because of something her colleague Yamazoe does. But it also turns out that Yamazoe, seemingly unmotivated despite having just changed jobs, suffers from anxiety disorder, has given up on things, is burned out and lost the will to live. Supported by understanding workplace colleagues, they develop a special feeling toward each other that is neither friend nor lover but more like comrade. Before you know it, they each start to think that even if their own condition doesn’t improve, they may be able to help the other.